Control of metabolic pathways
(b) Control of metabolic pathways (presence or absence of particular enzymes and the regulation of the rate of reaction of key enzymes within the pathway).
(i) Induced fit and the role of the active site of enzymes including shape and substrate affinity and orientation of reactants. Products have a low affinity for the active site. Activation energy. The effects of substrate and end product concentration on the direction and rate of enzyme reactions. Enzymes often act in groups or as multi-enzyme complexes.
(ii) Control of metabolic pathways through competitive, non-competitive and feedback inhibition of enzymes.
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Homework Sheets : CfE Higher Sht2_3
