The following questions have been selected to test and consolidate your learning in this area of the CfE Higher syllabus. They will also help you understand the style of question you may encounter in your final exam. The answers for each question can be accessed by clicking to reveal. At the bottom of the section are the relevant homework sheets for this section. The answers can be accessed by clicking the marking guide link. Remember, practice in applying your learning is key to building your confidence and knowledge and improving your eaxm success.
Advanced Subsidiary
Unit 1: Lifestyle, Transport, Genes and Health
Tuesday 11 January 2011 – Morning
Time: 1 hour 30 minutes
You do not need any other materials.
6BI01/01
Enzymes, messenger RNA (mRNA) and transfer RNA (tRNA) are involved in the synthesis of proteins.
(a) The diagram below represents the structure of an enzyme. Each circle represents an amino acid.
(i) An enzyme is a protein and has a primary structure.
Explain the meaning of the term primary structure.
(ii) Using the diagram and your own knowledge of enzymes, explain the importance of the primary structure of an enzyme to its function.
(b) Describe the roles of messenger RNA (mRNA) and transfer RNA (tRNA) in protein synthesis.
(i) Messenger RNA
(ii) Transfer RNA
//
2. joined by peptide bonds ;
(ii). 1. idea that primary structure determines (three-dimensional) folding or equivalent;
2. reference to types of amino acids determine {types of bonds / (other than peptide bonds)
/ named bond};
3. reference to position of amino acids determines position of{bonds / correctly named bond} ;
5. idea that {shape / position / eq} of active siteis determined by position of amino acids ;
6. reference to shape of active site being correct to bind to substrate ;b) .
![Picture5](https://hyndland-sec-glasgow.blogs.rm.com/wp_domains/16286_b/wp-content/uploads/sites/49/2014/05/Picture5.png)
![Picture6](https://hyndland-sec-glasgow.blogs.rm.com/wp_domains/16286_b/wp-content/uploads/sites/49/2014/05/Picture6.png)
1. idea that primary structure determines
(three-dimensional) folding / eq ;
Edexcel GCE
Biology
Advanced Subsidiary
Unit 1: Lifestyle, Transport, Genes and Health
Tuesday 12 January 2010 – Morning
Time: 1 hour 30 minutes
You do not need any other materials.
6BI01/01
2 Read through the following passage on protein synthesis, then write on the dotted
lines the most appropriate word or words to complete the passage.
(6)
Protein synthesis involves two stages. The first stage is ……………………………………………………….. and
takes place in the nucleus of the cell. During this stage, a molecule called
……………………………………………………….. is made using the antisense DNA strand as a template.
The second stage, known as ……………………………………………………….. , takes place in the cytoplasm of
the cell on structures called ……………………………………………………….. . During this stage,
……………………………………………………….. molecules enable the amino acids attached to them to line
up in the correct order. The amino acids are joined together by the formation of
……………………………………………………….. bonds.
……………………………………………………………………………………………………………….